Agnès Pérez-Millan

Barcelona, Spain · aperezmill@uoc.edu

Hello, I’m Agnès!

I am a Physicist with a MSc in Bioinformatics and Biostatistics and a PhD in Neuroscience. I am Assistant Professor and researcher at Universitat Oberta de Catalunya (UOC). I am a researcher at the Alzheimer’s Disease and Other Cognitive Disorders Unit at the Hospital Clínic de Barcelona-IDIBAPS. Also, I am participating in multiple outreach projects: Ciència Oberta, Neurones Fregides, and Píndoles Científiques.

I am focused on neurodegenerative diseases (basically Alzheimer’s Disease and frontotemporal dementia) with predictive modeling, machine learning, and biostatistics. I apply predictive modeling, machine learning algorithms, and advanced statistical analyses to predict or classify these neurodegenerative diseases and their phenotypes. I am focused on finding key biomarkers to differentiate these dementias and their phenotypes. Also, I’m trying to define disease trajectories according to age to study the prognosis of the patients.

Update: September 2024

Socialization

Publications

Article - Beyond group classification: Probabilistic differential diagnosis of frontotemporal dementia and Alzheimer’s disease with MRI and CSF biomarkers

Agnès Pérez-Millan, Bertrand Thirion, Neus Falgàs, Sergi Borrego-Écija, Beatriz Bosch, Jordi Juncà-Parella, Adrià Tort-Merino, Jordi Sarto, Josep Maria Augé, Anna Antonell, Nuria Bargalló, Mircea Balasa, Albert Lladó, Raquel Sánchez-Valle, Roser Sala-Llonch.

August 2024

Article - Locus coeruleus integrity and neuropsychiatric symptoms in a cohort of early-and late-onset Alzheimer’s disease

Neus Falgàs, Marta Peña-González, Andrea Val-Guardiola, Agnès Pérez-Millan, Núria Guillén, Jordi Sarto, Diana Esteller, Beatriz Bosch, Guadalupe Fernández-Villullas, Adrià Tort-Merino, Gerard Mayà, Josep Maria Augé, Alex Iranzo, Mircea Balasa, Albert Lladó, Manuel Morales-Ruiz, Núria Bargalló, Emma Muñoz-Moreno, Lea T Grinberg, Raquel Sánchez-Valle.

July 2024

Article - Increase in wasteosomes (corpora amylacea) in frontotemporal lobar degeneration with specific detection of tau, TDP-43 and FUS pathology

Raquel Alsina, Marta Riba, Agnès Pérez-Millan, Sergi Borrego-Écija, Iban Aldecoa, Clara Romera, Mircea Balasa, Anna Antonell, Albert Lladó, Yaroslau Compta, Jaume Del Valle, Raquel Sánchez-Valle, Carme Pelegrí, Laura Molina-Porcel, Jordi Vilaplana.

June 2024

Article - Cognitive profile, neuroimaging and fluid biomarkers in post-acute COVID-19 syndrome

Núria Guillén*, Agnès Pérez-Millan*, Neus Falgàs, Gema M Lledó-Ibáñez, Lorena Rami, Jordi Sarto, Maria A Botí, Cristina Arnaldos-Pérez, Raquel Ruiz-García, Laura Naranjo, Bàrbara Segura, Mircea Balasa, Roser Sala-Llonch, Albert Lladó, Sarah M Gray, Jason K Johannesen, Madeline M Pantoni, Grant A Rutledge, Ruta Sawant, Yi Wang, Luke S Watson, Josep Dalmau, Raquel Sánchez‐Valle. (* equivalent contribution).

June 2024

Article - Impact of demographics and comorbid conditions on plasma biomarkers concentrations and their diagnostic accuracy in a memory clinic cohort

Jordi Sarto, Diana Esteller-Gauxax, Adrià Tort-Merino, Núria Guillén, Agnès Pérez-Millan, Neus Falgàs, Sergi Borrego-Écija, Guadalupe Fernández-Villullas, Beatriz Bosch, Jordi Juncà-Parella, Anna Antonell, Laura Naranjo, Raquel Ruiz-García, Josep María Augé, Raquel Sánchez-Valle, Albert Lladó, Mircea Balasa.

April 2024

Article - Cortical thickness modeling and variability in Alzheimer’s disease and frontotemporal dementia

Agnès Pérez-Millan, Sergi Borrego-Écija, Neus Falgàs, Jordi Juncà-Parella, Beatriz Bosch, Adrià Tort-Merino, Anna Antonell, Nuria Bargalló, Lorena Rami, Mircea Balasa, Albert Lladó, Roser Sala-Llonch, Raquel Sánchez-Valle.

March 2024

Article - Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity

Sergi Borrego–Écija*, Agnès Pérez‐Millan*, Anna Antonell, Laura Fort‐Aznar, Elif Kaya‐Tilki, Alberto León‐Halcón, Albert Lladó, Laura Molina‐Porcel, Mircea Balasa, Jordi Juncà‐Parella, Javier Vitorica, Jose Luis Venero, Tomas Deierborg, Antonio Boza‐Serrano, Raquel Sánchez‐Valle. (* equivalent contribution).

March 2024

Article - Classifying Alzheimer’s disease and frontotemporal dementia using machine learning with cross‐sectional and longitudinal magnetic resonance imaging data

Agnès Pérez‐Millan, José Contador, Jordi Juncà‐Parella, Beatriz Bosch, Laia Borrell, Adrià Tort‐Merino, Neus Falgàs, Sergi Borrego‐Écija, Nuria Bargalló, Lorena Rami, Mircea Balasa, Albert Lladó, Raquel Sánchez‐Valle, Roser Sala‐Llonch.

January 2023

Article - Sex differences in early-onset Alzheimer’s disease

José Contador*, Agnès Pérez-Millan*, Nuria Guillen, Jordi Sarto, Adrià Tort-Merino, Mircea Balasa, Neus Falgàs, Magdalena Castellví, Sergi Borrego-Écija, Jordi Juncà-Parella, Beatriz Bosch, Guadalupe Fernández-Villullas, Oscar Ramos-Campoy, Anna Antonell, Nuria Bargalló, Raquel Sanchez-Valle, Roser Sala Llonch, Albert Lladó (* equivalent contribution).

November 2022

Article - Longitudinal brain atrophy and CSF biomarkers in early-onset Alzheimer’s disease

José Contador, Agnès Pérez-Millán, Adrià Tort-Merino, Mircea Balasa, Neus Falgàs, Jaume Olives, Magdalena Castellví, Sergi Borrego-Écija, Beatriz Bosch, Guadalupe Fernández-Villullas, Oscar Ramos-Campoy, Anna Antonell, Nuria Bargalló, Raquel Sanchez-Valle, Roser Sala-Llonch, Albert Lladó, Alzheimer's Disease Neuroimaging Initiative.

August 2021

Article - Contribution of CSF biomarkers to early-onset Alzheimer’s disease and frontotemporal dementia neuroimaging signatures

Neus Falgàs, Mariona Ruiz‐Peris, Agnès Pérez‐Millan, Roser Sala‐Llonch, Anna Antonell, Mircea Balasa, Sergi Borrego‐Écija, Oscar Ramos‐Campoy, Josep Maria Augé, Magdalena Castellví, Adrià Tort‐Merino, Jaume Olives, Guadalupe Fernández‐Villullas, Kaj Blennow, Henrik Zetterberg, Núria Bargalló, Albert Lladó, Raquel Sánchez‐Valle.

January 2020

See all Publications

Conferences

Poster - XXVIII Reunió Anual Societat Catalana de Neurologia

Asimetria cortical en individus en risc de patir malaltia d'Alzheimer

May 2024

Oral - Down Syndrome associated Alzheimer disease (DSAD) and autosomal dominant AD (ADAD)

Cortical Asymmetry in individuals with Autosomal Dominant Alzheimer’s Disease

April 2024

Oral - Down Syndrome associated Alzheimer disease (DSAD) and autosomal dominant AD (ADAD)

Galectin-3 is upregulated and correlated with MRI findings in Autosomal Dominant Alzheimer’s Disease and Genetic Frontotemporal Dementia

April 2024

Oral - VII Jornadas científicas de estudiantes de la SEB

The Cortical Asymmetry Index (CAI) for subtyping frontotemporal dementia and Alzheimer's disease patients

February 2024

Poster - OHBM 2023 ANNUAL MEETING

Probabilistic classification of Alzheimer’s Disease and Frontotemporal Dementia.

July 2023

Poster - AAIC 2023

Exploring the relationship between MRI changes and cognitive/neuropsychiatric complaints in a cohort of long COVID-19 patients. A cross-sectional and longitudinal study.

July 2023

See all Conferences

Education

University of Barcelona

PhD in Biomedicine, Cum Laude

2020 - 2023

Inria

Visiting PhD Student at MIND Team

October – November 2022

Medical University of Innsbruck

Eurolife Pilot School course: Data Ethics - Ethical considerations in interpretation and handling of Biomedical Big Data

April 2021

University of Göttingen

Erasmus+ Strategic Partnership grant towards DATAETHICS – Changing Landscapes in the Health and Life Sciences: Ethical Challenges of Biomedical Big Data (BBD)

February – March 2020