Agnès Pérez-Millan

Barcelona, Spain · agperez@recerca.clinic.cat

Hello, I’m Agnès!

I am a Physicist with a MSc in Bioinformatics and Biostatistics and a PhD in Neuroscience. I am a post-doctoral researcher at the Alzheimer’s Disease and Other Cognitive Disorders Unit at the Hospital Clínic de Barcelona. Also, I’m a teaching assistant for physics courses at the Polytechnic University of Catalonia (UPC). I participated in multiple outreach projects: Ciència Oberta, Neurones Fregides, and Píndoles Científiques.

I am focused on neurodegenerative diseases (basically Alzheimer’s Disease and frontotemporal dementia) with predictive modeling, machine learning, and biostatistics. I apply predictive modeling, machine learning algorithms, and advanced statistical analyses to predict or classify these neurodegenerative diseases and their phenotypes. I am focused on finding key biomarkers to differentiate these dementias and their phenotypes. Also, I’m trying to define disease trajectories according to age to study the prognosis of the patients.

Update: February 2024

Socialization

Publications

Article - Impact of demographics and comorbid conditions on plasma biomarkers concentrations and their diagnostic accuracy in a memory clinic cohort

Jordi Sarto, Diana Esteller-Gauxax, Adrià Tort-Merino, Núria Guillén, Agnès Pérez-Millan, Neus Falgàs, Sergi Borrego-Écija, Guadalupe Fernández-Villullas, Beatriz Bosch, Jordi Juncà-Parella, Anna Antonell, Laura Naranjo, Raquel Ruiz-García, Josep María Augé, Raquel Sánchez-Valle, Albert Lladó, Mircea Balasa.

December 2023

Article - Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity

Sergi Borrego–Écija*, Agnès Pérez‐Millan*, Anna Antonell, Laura Fort‐Aznar, Elif Kaya‐Tilki, Alberto León‐Halcón, Albert Lladó, Laura Molina‐Porcel, Mircea Balasa, Jordi Juncà‐Parella, Javier Vitorica, Jose Luis Venero, Tomas Deierborg, Antonio Boza‐Serrano, Raquel Sánchez‐Valle. (* equivalent contribution).

November 2023

Article - Cortical thickness modeling and variability in Alzheimer’s disease and frontotemporal dementia

Agnès Pérez-Millan, Sergi Borrego-Écija, Neus Falgàs, Jordi Juncà-Parella, Beatriz Bosch, Adrià Tort-Merino, Anna Antonell, Nuria Bargalló, Lorena Rami, Mircea Balasa, Albert Lladó, Roser Sala-Llonch, Raquel Sánchez-Valle.

November 2023

Article - Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study

Agnès Pérez-Millan*, Sergi Borrego-Écija*, John C van Swieten, Lize Jiskoot, Fermin Moreno, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Chris R Butler, Alexander Gerhard, Simon Ducharme, Isabelle Le Ber, Isabel Santana, Florence Pasquier, Johannes Levin, Markus Otto, Sandro Sorbi, Pietro Tiraboschi, Harro Seelaar, Tobias Langheinrich, Jonathan D Rohrer, Roser Sala-Llonch, Raquel Sánchez-Valle & The Genetic FTD Initiative, GENFI (* equivalent contribution).

March 2023

Article - The APOE4 effect: structural brain differences in Alzheimer’s disease according to the age at symptom onset

Gonzalo Forno, Jose Contador, Agnès Pérez‐Millan, Nuria Guillen, Neus Falgàs, Jordi Sarto, Adrià Tort‐Merino, Magdalena Castellví, Beatriz Bosch, Guadalupe Fernández‐Villullas, Mircea Balasa, Anna Antonell, Roser Sala‐Llonch, Raquel Sanchez‐Valle, Michael Hornberger, Albert Lladó.

February 2023

Article - Design and validation of the 1-week memory battery for assessing episodic memory and accelerated long-term forgetting in cognitively unimpaired subjects.

Lorena Rami, María León, Natalia Valech, Nina Coll-Padrós, Beatriz Bosch, Jaume Olives, Ana Salinero, Agnès Pérez-Millan, José Luis Molinuevo, Raquel Sánchez-Valle, Adrià Tort-Merino.

February 2023

Article - Classifying Alzheimer’s disease and frontotemporal dementia using machine learning with cross‐sectional and longitudinal magnetic resonance imaging data

Agnès Pérez‐Millan, José Contador, Jordi Juncà‐Parella, Beatriz Bosch, Laia Borrell, Adrià Tort‐Merino, Neus Falgàs, Sergi Borrego‐Écija, Nuria Bargalló, Lorena Rami, Mircea Balasa, Albert Lladó, Raquel Sánchez‐Valle, Roser Sala‐Llonch.

January 2023

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Conferences

Poster - OHBM 2023 ANNUAL MEETING

Probabilistic classification of Alzheimer’s Disease and Frontotemporal Dementia.

July 2023

Poster - AAIC 2023

Exploring the relationship between MRI changes and cognitive/neuropsychiatric complaints in a cohort of long COVID-19 patients. A cross-sectional and longitudinal study.

July 2023

Poster - AAIC 2023

Probabilistic computer-aided diagnosis of Alzheimer’s disease and frontotemporal dementia based on MRI and biochemical markers.

July 2023

Oral - Emerging Topics in Artificial Intelligence (ETAI) 2022

Classification between Early Onset Alzheimer's disease and frontotemporal dementia using a single neuroimaging feature.

August 2022

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Education

University of Barcelona

PhD in Biomedicine, Cum Laude

2020 - 2023

Inria

Visiting PhD Student at MIND Team

October – November 2022

Medical University of Innsbruck

Eurolife Pilot School course: Data Ethics - Ethical considerations in interpretation and handling of Biomedical Big Data

April 2021

University of Göttingen

Erasmus+ Strategic Partnership grant towards DATAETHICS – Changing Landscapes in the Health and Life Sciences: Ethical Challenges of Biomedical Big Data (BBD)

February – March 2020